Mary Isham
- Yes, date unknown
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| Thomas Jefferson | |
| B: | 13 Apr 1743 |
| Shadwell Plantation, VA, USA | |
| D: | 4 Jul 1826 |
| Monticello, VA | |
| Martha Wayles Skelton | |
| B: | 1748 |
| M: | 1 Jan 1772 |
| D: | 1782 |
| Jane Randolph | |
| D: | Yes, date unknown |
| Peter Jefferson | |
| D: | Yes, date unknown |
| Isham Randolph | |
| D: | Yes, date unknown |
| Jane Rogers | |
| D: | Yes, date unknown |
| Mary Isham | |
| D: | Yes, date unknown |
| William Randolph | |
| D: | Yes, date unknown |